High-resolution analysis of multi-copy variant surface glycoprotein gene expression sites in African trypanosomes

Por Hutchinson, Sebastian, Glover, Lucy, Horn, David
Publicado no BMC Genomics (2016)

VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

Por Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, Horn, David
Publicado no Proc Natl Acad Sci U S A (2016)

A post-transcriptional respiratome regulon in trypanosomes

Por Trenaman, Anna, Glover, Lucy, Hutchinson, Sebastian, Horn, David
Publicado no Nucleic Acids Res (2019)

Escaping the immune system by DNA repair and recombination in African trypanosomes

Por Sima, Núria, McLaughlin, Emilia Jane, Hutchinson, Sebastian, Glover, Lucy
Publicado no Open Biol (2019)

Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

Por Faria, Joana, Glover, Lucy, Hutchinson, Sebastian, Boehm, Cordula, Field, Mark C., Horn, David
Publicado no Nat Commun (2019)

Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

Por Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, McCulloch, Richard, Field, Mark C, Horn, David
Publicado em 2013

Vacuolar ATPase depletion affects mitochondrial ATPase function, kinetoplast dependency, and drug sensitivity in trypanosomes

Por Baker, Nicola, Hamilton, Graham, Wilkes, Jonathan M., Hutchinson, Sebastian, Barrett, Michael P., Horn, David
Publicado no Proc Natl Acad Sci U S A (2015)

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

Por Thomas, James A., Baker, Nicola, Hutchinson, Sebastian, Dominicus, Caia, Trenaman, Anna, Glover, Lucy, Alsford, Sam, Horn, David
Publicado no PLoS Negl Trop Dis (2018)

Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei

Por Collett, Clare F., Kitson, Carl, Baker, Nicola, Steele-Stallard, Heather B., Santrot, Marie-Victoire, Hutchinson, Sebastian, Horn, David, Alsford, Sam
Publicado no Antimicrob Agents Chemother (2019)

Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

Por Zhang, Ning, Zoltner, Martin, Leung, Ka-Fai, Scullion, Paul, Hutchinson, Sebastian, del Pino, Ricardo C., Vincent, Isabel M., Zhang, Yong-Kang, Freund, Yvonne R., Alley, Michael R. K., Jacobs, Robert T., Read, Kevin D., Barrett, Michael P., Horn, David, Field, Mark C.
Publicado no PLoS Pathog (2018)

Biallelic Mutations in LRRC56, Encoding a Protein Associated with Intraflagellar Transport, Cause Mucociliary Clearance and Laterality Defects

Por Bonnefoy, Serge, Watson, Christopher M., Kernohan, Kristin D., Lemos, Moara, Hutchinson, Sebastian, Poulter, James A., Crinnion, Laura A., Berry, Ian, Simmonds, Jennifer, Vasudevan, Pradeep, O’Callaghan, Chris, Hirst, Robert A., Rutman, Andrew, Huang, Lijia, Hartley, Taila, Grynspan, David, Moya, Eduardo, Li, Chunmei, Carr, Ian M., Bonthron, David T., Leroux, Michel, Boycott, Kym M., Bastin, Philippe, Sheridan, Eamonn G.
Publicado no Am J Hum Genet (2018)