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Escaping the immune system by DNA repair and recombination in African trypanosomes

African trypanosomes escape the mammalian immune response by antigenic variation—the periodic exchange of one surface coat protein, in Trypanosoma brucei the variant surface glycoprotein (VSG), for an immunologically distinct one. VSG transcription is monoallelic, with only one VSG being expressed a...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Sima, Núria, McLaughlin, Emilia Jane, Hutchinson, Sebastian, Glover, Lucy
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893398/
https://ncbi.nlm.nih.gov/pubmed/31718509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190182
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