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Escaping the immune system by DNA repair and recombination in African trypanosomes

African trypanosomes escape the mammalian immune response by antigenic variation—the periodic exchange of one surface coat protein, in Trypanosoma brucei the variant surface glycoprotein (VSG), for an immunologically distinct one. VSG transcription is monoallelic, with only one VSG being expressed a...

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Detalles Bibliográficos
Publicado en:Open Biol
Autores principales: Sima, Núria, McLaughlin, Emilia Jane, Hutchinson, Sebastian, Glover, Lucy
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893398/
https://ncbi.nlm.nih.gov/pubmed/31718509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190182
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