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Escaping the immune system by DNA repair and recombination in African trypanosomes

African trypanosomes escape the mammalian immune response by antigenic variation—the periodic exchange of one surface coat protein, in Trypanosoma brucei the variant surface glycoprotein (VSG), for an immunologically distinct one. VSG transcription is monoallelic, with only one VSG being expressed a...

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Vydáno v:Open Biol
Hlavní autoři: Sima, Núria, McLaughlin, Emilia Jane, Hutchinson, Sebastian, Glover, Lucy
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893398/
https://ncbi.nlm.nih.gov/pubmed/31718509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190182
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