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The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes

Homologous recombination dominates as the major form of DNA repair in Trypanosoma brucei, and is especially important for recombination of the subtelomeric variant surface glycoprotein during antigenic variation. RAD50, a component of the MRN complex (MRE11, RAD50, NBS1), is central to homologous re...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Mehnert, Ann-Kathrin, Prorocic, Marco, Dujeancourt-Henry, Annick, Hutchinson, Sebastian, McCulloch, Richard, Glover, Lucy
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897489/
https://ncbi.nlm.nih.gov/pubmed/33450001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1265
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