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The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes
Homologous recombination dominates as the major form of DNA repair in Trypanosoma brucei, and is especially important for recombination of the subtelomeric variant surface glycoprotein during antigenic variation. RAD50, a component of the MRN complex (MRE11, RAD50, NBS1), is central to homologous re...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7897489/ https://ncbi.nlm.nih.gov/pubmed/33450001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1265 |
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