Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei

The arsenal of drugs used to treat leishmaniasis, caused by Leishmania spp., is limited and beset by toxicity and emergent resistance. Furthermore, our understanding of drug mode of action and potential routes to resistance is limited. Forward genetic approaches have revolutionized our understanding...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Collett, Clare F., Kitson, Carl, Baker, Nicola, Steele-Stallard, Heather B., Santrot, Marie-Victoire, Hutchinson, Sebastian, Horn, David, Alsford, Sam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658743/
https://ncbi.nlm.nih.gov/pubmed/31160283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00795-19
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