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Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor

Avibactam is a β-lactamase inhibitor that is in clinical development, combined with β-lactam partners, for the treatment of bacterial infections comprising Gram-negative organisms. Avibactam is a structural class of inhibitor that does not contain a β-lactam core but maintains the capacity to covale...

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Autors principals: Ehmann, David E., Jahić, Haris, Ross, Philip L., Gu, Rong-Fang, Hu, Jun, Kern, Gunther, Walkup, Grant K., Fisher, Stewart L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406822/
https://ncbi.nlm.nih.gov/pubmed/22753474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205073109
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