Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?

Based upon knowledge of the hydrolytic profile of major β-lactamases found in Gram-negative bacteria, we tested the efficacy of the combination of ceftazidime-avibactam (CAZ-AVI) with aztreonam (ATM) against carbapenem-resistant enteric bacteria possessing metallo-β-lactamases (MBLs). Disk diffusion...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Marshall, Steven, Hujer, Andrea M., Rojas, Laura J., Papp-Wallace, Krisztina M., Humphries, Romney M., Spellberg, Brad, Hujer, Kristine M., Marshall, Emma K., Rudin, Susan D., Perez, Federico, Wilson, Brigid M., Wasserman, Ronald B., Chikowski, Linda, Paterson, David L., Vila, Alejandro J., van Duin, David, Kreiswirth, Barry N., Chambers, Henry F., Fowler, Vance G., Jacobs, Michael R., Pulse, Mark E., Weiss, William J., Bonomo, Robert A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Susceptibility
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365724/
https://ncbi.nlm.nih.gov/pubmed/28167541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02243-16
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