1385. Efficacy of Ceftazidime–Avibactam in Combination with Aztreonam (COMBINE): Solutions for Metallo-β-Lactamase Producing-Enterobacteriaceae (MBL)

BACKGROUND: Novel antibiotics will not be available to combat the threat of MBLs until 2021. One strategy to overcome MBLs is to combine CAZ-AVI + ATM. ATM is not hydrolysed by MBLs and AVI offers protection for ATM and CAZ vs. ESBLs and AmpCs. The combination also offers a theoretical advantage to...

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Dettagli Bibliografici
Pubblicato in:Open Forum Infect Dis
Autori principali: Lodise, Thomas P, Smith, Nicholas M, Holden, Patricia, O’Donnell, J Nicholas, Bedard, Tyler, Bonomo, Robert A, Tsuji, Brian T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252595/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1216
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