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2443. Searching for the Optimal Treatment Regimen for Metallo-β-Lactamase Producing Enterobacteriaceae: Aztreonam Plus Ceftazidime–Avibactam vs. Aztreonam Plus Meropenem–Vaborbactam

BACKGROUND: Pathogens harboring metallo-β-lactamase (MBL) enzymes pose a large threat to public health. Aztreonam (ATM) is not hydrolyzed by MBLs but is inactivated by other β-lactamases, which are often co-harbored in MBL-producers. Ceftazidime/avibactam (CAZ/AVI) and meropenem/vaborbactam (MER/VBR...

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Bibliographische Detailangaben
Veröffentlicht in:Open Forum Infect Dis
Hauptverfasser: Biagi, Mark, Wenzler, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254777/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.2096
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