Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?

Based upon knowledge of the hydrolytic profile of major β-lactamases found in Gram-negative bacteria, we tested the efficacy of the combination of ceftazidime-avibactam (CAZ-AVI) with aztreonam (ATM) against carbapenem-resistant enteric bacteria possessing metallo-β-lactamases (MBLs). Disk diffusion...

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Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Marshall, Steven, Hujer, Andrea M., Rojas, Laura J., Papp-Wallace, Krisztina M., Humphries, Romney M., Spellberg, Brad, Hujer, Kristine M., Marshall, Emma K., Rudin, Susan D., Perez, Federico, Wilson, Brigid M., Wasserman, Ronald B., Chikowski, Linda, Paterson, David L., Vila, Alejandro J., van Duin, David, Kreiswirth, Barry N., Chambers, Henry F., Fowler, Vance G., Jacobs, Michael R., Pulse, Mark E., Weiss, William J., Bonomo, Robert A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Susceptibility
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365724/
https://ncbi.nlm.nih.gov/pubmed/28167541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02243-16
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