Improved synthesis of UDP-2-(2-ketopropyl)galactose and a first synthesis of UDP-2-(2-ketopropyl)glucose for the site-specific linking of biomolecules via modified glycan residues...

Por Dulcey, Andrés E., Qasba, Pradman K., Lamb, Jeffrey, Griffiths, Gary L.
Publicado em 2011

Principles of self-assembly of helical pores from dendritic dipeptides

Por Percec, Virgil, Dulcey, Andrés E., Peterca, Mihai, Ilies, Monica, Nummelin, Sami, Sienkowska, Monika J., Heiney, Paul A.
Publicado em 2006

The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2

Por Pasek, Marta, Ramakrishnan, Boopathy, Boeggeman, Elizabeth, Mercer, Natalia, Dulcey, Andres E, Griffiths, Gary L, Qasba, Pradman K
Publicado em 2012

A Selective TSH Receptor Antagonist Inhibits Stimulation of Thyroid Function in Female Mice

Por Neumann, Susanne, Nir, Eshel A., Eliseeva, Elena, Huang, Wenwei, Marugan, Juan, Xiao, Jingbo, Dulcey, Andrés E., Gershengorn, Marvin C.
Publicado em 2014

Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway

Por Contreras, Pablo S., Gonzalez-Zuñiga, Marcelo, González-Hódar, Lila, Yáñez, María José, Dulcey, Andrés, Marugan, Juan, Seto, Edward, Alvarez, Alejandra R., Zanlungo, Silvana
Publicado no Biochim Biophys Acta (2015)

Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK

Por Dai, Sheng, Dulcey, Andrés E., Hu, Xin, Wassif, Christopher A., Porter, Forbes D., Austin, Christopher P., Ory, Daniel S., Marugan, Juan, Zheng, Wei
Publicado no Autophagy (2017)

Collateral Sensitivity of Multidrug-Resistant Cells to the Orphan Drug Tiopronin

Por Goldsborough, Andrew S., Handley, Misty D., Dulcey, Andrés E., Pluchino, Kristen M., Kannan, Pavitra, Brimacombe, Kyle R., Hall, Matthew D., Griffiths, Gary, Gottesman, Michael M.
Publicado em 2011

Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection

Por He, Shanshan, Xiao, Jingbo, Dulcey, Andrés E., Lin, Billy, Rolt, Adam, Hu, Zongyi, Hu, Xin, Wang, Amy Q., Xu, Xin, Southall, Noel, Ferrer, Marc, Zheng, Wei, Liang, T. Jake, Marugan, Juan J.
Publicado no J Med Chem (2015)

Inhibition of Glutathione Peroxidase Mediates the Collateral Sensitivity of Multidrug-resistant Cells to Tiopronin

Por Hall, Matthew D., Marshall, Travis S., Kwit, Alexandra D. T., Miller Jenkins, Lisa M., Dulcey, Andrés E., Madigan, James P., Pluchino, Kristen M., Goldsborough, Andrew S., Brimacombe, Kyle R., Griffiths, Gary L., Gottesman, Michael M.
Publicado em 2014

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus

Por Mukhopadhyay, Rupkatha, Roy, Sujayita, Venkatadri, Rajkumar, Su, Yu-Pin, Ye, Wenjuan, Barnaeva, Elena, Mathews Griner, Lesley, Southall, Noel, Hu, Xin, Wang, Amy Q., Xu, Xin, Dulcey, Andrés E., Marugan, Juan J., Ferrer, Marc, Arav-Boger, Ravit
Publicado no PLoS Pathog (2016)

Discovery, Optimization, and Characterization of Novel D(2) Dopamine Receptor Selective Antagonists

Por Xiao, Jingbo, Free, R. Benjamin, Barnaeva, Elena, Conroy, Jennie L., Doyle, Trevor, Miller, Brittney, Bryant-Genevier, Marthe, Taylor, Mercedes K., Hu, Xin, Dulcey, Andrés E., Southall, Noel, Ferrer, Marc, Titus, Steve, Zheng, Wei, Sibley, David R., Marugan, Juan J.
Publicado no J Med Chem (2014)

Discovery and Characterization of a G Protein–Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor

Por Free, R. Benjamin, Chun, Lani S., Moritz, Amy E., Miller, Brittney N., Doyle, Trevor B., Conroy, Jennie L., Padron, Adrian, Meade, Julie A., Xiao, Jingbo, Hu, Xin, Dulcey, Andrés E., Han, Yang, Duan, Lihua, Titus, Steve, Bryant-Genevier, Melanie, Barnaeva, Elena, Ferrer, Marc, Javitch, Jonathan A., Beuming, Thijs, Shi, Lei, Southall, Noel T., Marugan, Juan J., Sibley, David R.
Publicado em 2014

SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy

Por Sarathy, Apurva, Wuebbles, Ryan D., Fontelonga, Tatiana M., Tarchione, Ashley R., Mathews Griner, Lesley A., Heredia, Dante J., Nunes, Andreia M., Duan, Suzann, Brewer, Paul D., Van Ry, Tyler, Hennig, Grant W., Gould, Thomas W., Dulcey, Andrés E., Wang, Amy, Xu, Xin, Chen, Catherine Z., Hu, Xin, Zheng, Wei, Southall, Noel, Ferrer, Marc, Marugan, Juan, Burkin, Dean J.
Publicado no Mol Ther (2017)