Inhibition of Glutathione Peroxidase Mediates the Collateral Sensitivity of Multidrug-resistant Cells to Tiopronin

Multidrug resistance (MDR) is a major obstacle to the successful chemotherapy of cancer. MDR is often the result of overexpression of ATP-binding cassette transporters following chemotherapy. A common ATP-binding cassette transporter that is overexpressed in MDR cancer cells is P-glycoprotein, which...

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Bibliografski detalji
Glavni autori: Hall, Matthew D., Marshall, Travis S., Kwit, Alexandra D. T., Miller Jenkins, Lisa M., Dulcey, Andrés E., Madigan, James P., Pluchino, Kristen M., Goldsborough, Andrew S., Brimacombe, Kyle R., Griffiths, Gary L., Gottesman, Michael M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Cell Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118110/
https://ncbi.nlm.nih.gov/pubmed/24930045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.581702
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