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SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal muscle disease caused by mutations in the dystrophin gene, resulting in a complete loss of the dystrophin protein. Dystrophin is a critical component of the dystrophin glycoprotein complex (DGC), which links laminin in the extracellular matrix to the acti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther
Prif Awduron: Sarathy, Apurva, Wuebbles, Ryan D., Fontelonga, Tatiana M., Tarchione, Ashley R., Mathews Griner, Lesley A., Heredia, Dante J., Nunes, Andreia M., Duan, Suzann, Brewer, Paul D., Van Ry, Tyler, Hennig, Grant W., Gould, Thomas W., Dulcey, Andrés E., Wang, Amy, Xu, Xin, Chen, Catherine Z., Hu, Xin, Zheng, Wei, Southall, Noel, Ferrer, Marc, Marugan, Juan, Burkin, Dean J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474963/
https://ncbi.nlm.nih.gov/pubmed/28391962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.03.022
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