SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal muscle disease caused by mutations in the dystrophin gene, resulting in a complete loss of the dystrophin protein. Dystrophin is a critical component of the dystrophin glycoprotein complex (DGC), which links laminin in the extracellular matrix to the acti...

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發表在:Mol Ther
Main Authors: Sarathy, Apurva, Wuebbles, Ryan D., Fontelonga, Tatiana M., Tarchione, Ashley R., Mathews Griner, Lesley A., Heredia, Dante J., Nunes, Andreia M., Duan, Suzann, Brewer, Paul D., Van Ry, Tyler, Hennig, Grant W., Gould, Thomas W., Dulcey, Andrés E., Wang, Amy, Xu, Xin, Chen, Catherine Z., Hu, Xin, Zheng, Wei, Southall, Noel, Ferrer, Marc, Marugan, Juan, Burkin, Dean J.
格式: Artigo
語言:Inglês
出版: American Society of Gene & Cell Therapy 2017
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474963/
https://ncbi.nlm.nih.gov/pubmed/28391962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.03.022
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