Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by mutations in the dystrophin gene, leading to the loss of a critical component of the sarcolemmal dystrophin glycoprotein complex. Galectin-1 is a small 14 kDa protein normally found in skeletal muscle and has been shown to...

Full description

Saved in:
Bibliographic Details
Published in:Mol Ther
Main Authors: Van Ry, Pam M, Wuebbles, Ryan D, Key, Megan, Burkin, Dean J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817863/
https://ncbi.nlm.nih.gov/pubmed/26050991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.105
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items