Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by mutations in the dystrophin gene, leading to the loss of a critical component of the sarcolemmal dystrophin glycoprotein complex. Galectin-1 is a small 14 kDa protein normally found in skeletal muscle and has been shown to...

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Publicado en:Mol Ther
Autores principales: Van Ry, Pam M, Wuebbles, Ryan D, Key, Megan, Burkin, Dean J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817863/
https://ncbi.nlm.nih.gov/pubmed/26050991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.105
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