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Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease caused by mutations in the gene encoding dystrophin. Loss of dystrophin results in reduced sarcolemmal integrity and increased susceptibility to muscle damage. The α(7)β(1)-integrin is a laminin-binding protein up-regulated in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683113/ https://ncbi.nlm.nih.gov/pubmed/19416897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811599106 |
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