Structure of Class B GPCRs: new horizons for drug discovery

Yazar: Bortolato, Andrea, Doré, Andrew S, Hollenstein, Kaspar, Tehan, Benjamin G, Mason, Jonathan S, Marshall, Fiona H
Baskı/Yayın Bilgisi 2014

Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists

Yazar: Schöppe, Jendrik, Ehrenmann, Janosch, Klenk, Christoph, Rucktooa, Prakash, Schütz, Marco, Doré, Andrew S., Plückthun, Andreas
Yayımlandı Nat Commun (2019)

Molecular basis for high affinity agonist binding in GPCRs

Yazar: Warne, Tony, Edwards, Patricia C., Doré, Andrew S., Leslie, Andrew G. W., Tate, Christopher G.
Yayımlandı Science (2019)

Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal 
Structures

Yazar: Doré, Andrew S., Bortolato, Andrea, Hollenstein, Kaspar, Cheng, Robert K.Y., Read, Randy J., Marshall, Fiona H.
Yayımlandı Curr Mol Pharmacol (2017)

Structure of an archaeal PCNA1–PCNA2–FEN1 complex: elucidating PCNA subunit and client enzyme specificity

Yazar: Doré, Andrew S., Kilkenny, Mairi L., Jones, Sarah A., Oliver, Antony W., Roe, S. Mark, Bell, Stephen D., Pearl, Laurence H.
Baskı/Yayın Bilgisi 2006

Structural and functional analysis of the Crb2–BRCT(2) domain reveals distinct roles in checkpoint signaling and DNA damage repair

Yazar: Kilkenny, Mairi L., Doré, Andrew S., Roe, S. Mark, Nestoras, Konstantinos, Ho, Jenny C.Y., Watts, Felicity Z., Pearl, Laurence H.
Baskı/Yayın Bilgisi 2008

Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A(2A) Receptor crystals

Yazar: Rucktooa, Prakash, Cheng, Robert K. Y., Segala, Elena, Geng, Tian, Errey, James C., Brown, Giles A., Cooke, Robert M., Marshall, Fiona H., Doré, Andrew S.
Yayımlandı Sci Rep (2018)

Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design

Yazar: Congreve, Miles, Andrews, Stephen P., Doré, Andrew S., Hollenstein, Kaspar, Hurrell, Edward, Langmead, Christopher J., Mason, Jonathan S., Ng, Irene W., Tehan, Benjamin, Zhukov, Andrei, Weir, Malcolm, Marshall, Fiona H.
Baskı/Yayın Bilgisi 2012

Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine

Yazar: Doré, Andrew S., Robertson, Nathan, Errey, James C., Ng, Irene, Hollenstein, Kaspar, Tehan, Ben, Hurrell, Edward, Bennett, Kirstie, Congreve, Miles, Magnani, Francesca, Tate, Christopher G., Weir, Malcolm, Marshall, Fiona H.
Baskı/Yayın Bilgisi 2011

Biophysical Fragment Screening of the β(1)-Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design

Yazar: Christopher, John A., Brown, Jason, Doré, Andrew S., Errey, James C., Koglin, Markus, Marshall, Fiona H., Myszka, David G., Rich, Rebecca L., Tate, Christopher G., Tehan, Benjamin, Warne, Tony, Congreve, Miles
Baskı/Yayın Bilgisi 2013

Outrunning free radicals in room-temperature macromolecular crystallography

Yazar: Owen, Robin L., Axford, Danny, Nettleship, Joanne E., Owens, Raymond J., Robinson, James I., Morgan, Ann W., Doré, Andrew S., Lebon, Guillaume, Tate, Christopher G., Fry, Elizabeth E., Ren, Jingshan, Stuart, David I., Evans, Gwyndaf
Yayımlandı Acta Crystallogr D Biol Crystallogr (2012)

X‐Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A(2A) Adenosine Receptor Antagonists

Yazar: Jespers, Willem, Verdon, Grégory, Azuaje, Jhonny, Majellaro, Maria, Keränen, Henrik, García‐Mera, Xerardo, Congreve, Miles, Deflorian, Francesca, de Graaf, Chris, Zhukov, Andrei, Doré, Andrew S., Mason, Jonathan S., Åqvist, Johan, Cooke, Robert M., Sotelo, Eddy, Gutiérrez‐de‐Terán, Hugo
Yayımlandı Angew Chem Int Ed Engl (2020)

Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis

Yazar: Rappas, Mathieu, Ali, Ammar A. E., Bennett, Kirstie A., Brown, Jason D., Bucknell, Sarah J., Congreve, Miles, Cooke, Robert M., Cseke, Gabriella, de Graaf, Chris, Doré, Andrew S., Errey, James C., Jazayeri, Ali, Marshall, Fiona H., Mason, Jonathan S., Mould, Richard, Patel, Jayesh C., Tehan, Benjamin G., Weir, Malcolm, Christopher, John A.
Yayımlandı J Med Chem (2019)

Small molecule AZD4635 inhibitor of A(2A)R signaling rescues immune cell function including CD103(+) dendritic cells enhancing anti-tumor immunity

Yazar: Borodovsky, Alexandra, Barbon, Christine M, Wang, Yanjun, Ye, Minwei, Prickett, Laura, Chandra, Dinesh, Shaw, Joseph, Deng, Nanhua, Sachsenmeier, Kris, Clarke, James D, Linghu, Bolan, Brown, Giles A, Brown, James, Congreve, Miles, Cheng, Robert KY, Dore, Andrew S, Hurrell, Edward, Shao, Wenlin, Woessner, Richard, Reimer, Corinne, Drew, Lisa, Fawell, Stephen, Schuller, Alwin G, Mele, Deanna A
Yayımlandı J Immunother Cancer (2020)

Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons

Yazar: Weinert, Tobias, Olieric, Natacha, Cheng, Robert, Brünle, Steffen, James, Daniel, Ozerov, Dmitry, Gashi, Dardan, Vera, Laura, Marsh, May, Jaeger, Kathrin, Dworkowski, Florian, Panepucci, Ezequiel, Basu, Shibom, Skopintsev, Petr, Doré, Andrew S., Geng, Tian, Cooke, Robert M., Liang, Mengning, Prota, Andrea E., Panneels, Valerie, Nogly, Przemyslaw, Ermler, Ulrich, Schertler, Gebhard, Hennig, Michael, Steinmetz, Michel O., Wang, Meitian, Standfuss, Jörg
Yayımlandı Nat Commun (2017)

Advances in long-wavelength native phasing at X-ray free-electron lasers

Yazar: Nass, Karol, Cheng, Robert, Vera, Laura, Mozzanica, Aldo, Redford, Sophie, Ozerov, Dmitry, Basu, Shibom, James, Daniel, Knopp, Gregor, Cirelli, Claudio, Martiel, Isabelle, Casadei, Cecilia, Weinert, Tobias, Nogly, Przemyslaw, Skopintsev, Petr, Usov, Ivan, Leonarski, Filip, Geng, Tian, Rappas, Mathieu, Doré, Andrew S., Cooke, Robert, Nasrollahi Shirazi, Shahrooz, Dworkowski, Florian, Sharpe, May, Olieric, Natacha, Bacellar, Camila, Bohinc, Rok, Steinmetz, Michel O., Schertler, Gebhard, Abela, Rafael, Patthey, Luc, Schmitt, Bernd, Hennig, Michael, Standfuss, Jörg, Wang, Meitian, Milne, Christopher J.
Yayımlandı IUCrJ (2020)