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Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists
Neurokinins (or tachykinins) are peptides that modulate a wide variety of human physiology through the neurokinin G protein-coupled receptor family, implicated in a diverse array of pathological processes. Here we report high-resolution crystal structures of the human NK(1) receptor (NK(1)R) bound t...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6318301/ https://ncbi.nlm.nih.gov/pubmed/30604743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07939-8 |
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