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Directed evolution of G protein-coupled receptors in yeast for higher functional production in eukaryotic expression hosts
Despite recent successes, many G protein-coupled receptors (GPCRs) remained refractory to detailed molecular studies due to insufficient production yields, even in the most sophisticated eukaryotic expression systems. Here we introduce a robust method employing directed evolution of GPCRs in yeast t...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766470/ https://ncbi.nlm.nih.gov/pubmed/26911446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21508 |
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