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A generic selection system for improved expression and thermostability of G protein-coupled receptors by directed evolution
Structural and biophysical studies as well as drug screening approaches on G protein-coupled receptors (GPCRs) have been largely hampered by the poor biophysical properties and low expression yields of this largest class of integral membrane proteins. Thermostabilisation of GPCRs by introduction of...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4758055/ https://ncbi.nlm.nih.gov/pubmed/26887595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21294 |
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