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Crystal structure of the human oxytocin receptor

The peptide hormone oxytocin modulates socioemotional behavior and sexual reproduction via the centrally expressed oxytocin receptor (OTR) across several species. Here, we report the crystal structure of human OTR in complex with retosiban, a nonpeptidic antagonist developed as an oral drug for the...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Waltenspühl, Yann, Schöppe, Jendrik, Ehrenmann, Janosch, Kummer, Lutz, Plückthun, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439316/
https://ncbi.nlm.nih.gov/pubmed/32832646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb5419
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