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Crystal structure of the human oxytocin receptor

The peptide hormone oxytocin modulates socioemotional behavior and sexual reproduction via the centrally expressed oxytocin receptor (OTR) across several species. Here, we report the crystal structure of human OTR in complex with retosiban, a nonpeptidic antagonist developed as an oral drug for the...

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Pubblicato in:Sci Adv
Autori principali: Waltenspühl, Yann, Schöppe, Jendrik, Ehrenmann, Janosch, Kummer, Lutz, Plückthun, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439316/
https://ncbi.nlm.nih.gov/pubmed/32832646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb5419
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