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Structure of Class B GPCRs: new horizons for drug discovery

Class B GPCRs of the secretin family are important drug targets in many human diseases including diabetes, neurodegeneration, cardiovascular disease and psychiatric disorders. X-ray crystal structures for the glucagon receptor and corticotropin-releasing factor receptor 1 have now been published. In...

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Detalhes bibliográficos
Main Authors: Bortolato, Andrea, Doré, Andrew S, Hollenstein, Kaspar, Tehan, Benjamin G, Mason, Jonathan S, Marshall, Fiona H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080969/
https://ncbi.nlm.nih.gov/pubmed/24628305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12689
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