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An Overview on GPCRs and Drug Discovery: Structure-Based Drug Design and Structural Biology on GPCRs

G protein-coupled receptors (GPCRs) represent 50–60% of the current drug targets. There is no doubt that this family of membrane proteins plays a crucial role in drug discovery today. Classically, a number of drugs based on GPCRs have been developed for such different indications as cardiovascular,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:G Protein-Coupled Receptors in Drug Discovery
Prif Awdur: Lundstrom, Kenneth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7122359/
https://ncbi.nlm.nih.gov/pubmed/19513641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-317-6_4
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