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An Overview on GPCRs and Drug Discovery: Structure-Based Drug Design and Structural Biology on GPCRs
G protein-coupled receptors (GPCRs) represent 50–60% of the current drug targets. There is no doubt that this family of membrane proteins plays a crucial role in drug discovery today. Classically, a number of drugs based on GPCRs have been developed for such different indications as cardiovascular,...
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| Publicado no: | G Protein-Coupled Receptors in Drug Discovery |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7122359/ https://ncbi.nlm.nih.gov/pubmed/19513641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-317-6_4 |
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