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Insights into the structure of class B GPCRs

The secretin-like (class B) family of G protein-coupled receptors (GPCRs) are key players in hormonal homeostasis and are interesting drug targets for the treatment of several metabolic disorders (type 2 diabetes, osteoporosis, obesity) and nervous system diseases (migraine, anxiety, depression). Th...

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Bibliografske podrobnosti
Main Authors: Hollenstein, Kaspar, de Graaf, Chris, Bortolato, Andrea, Wang, Ming-Wei, Marshall, Fiona H., Stevens, Raymond C.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931419/
https://ncbi.nlm.nih.gov/pubmed/24359917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2013.11.001
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