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Structural and functional insights into the juxtamembranous amino-terminal tail and extracellular loop regions of class B GPCRs

Class B guanine nucleotide-binding protein GPCRs share heptahelical topology and signalling via coupling with heterotrimeric G proteins typical of the entire superfamily of GPCRs. However, they also exhibit substantial structural differences from the more extensively studied class A GPCRs. Even thei...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Dong, M, Koole, C, Wootten, D, Sexton, P M, Miller, L J
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Blackwell Publishing Ltd 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952790/
https://ncbi.nlm.nih.gov/pubmed/23889342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12293
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