Cellular and genetic models of H6PDH and 11β‐HSD1 function in skeletal muscle

by Zielinska, Agnieszka E., Fletcher, Rachel S., Sherlock, Mark, Doig, Craig L., Lavery, Gareth G.
Published in Cell Biochem Funct (2017)

Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells

by Doig, Craig L., Battaglia, Sebastiano, Khanim, Farhat L., Bunce, Christopher M., Campbell, Moray J.
Published in J Steroid Biochem Mol Biol (2015)

TNFα-mediated Hsd11b1 binding of NF-κB p65 is associated with suppression of 11β-HSD1 in muscle

by Doig, Craig L, Bashir, Jamila, Zielinska, Agnieszka E, Cooper, Mark S, Stewart, Paul M, Lavery, Gareth G
Published 2014

Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells

by Singh, Prashant K., Doig, Craig L., Dhiman, Vineet K., Turner, Bryan M., Smiraglia, Dominic J., Campbell, Moray J.
Published in J Steroid Biochem Mol Biol (2012)

Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism

by Morgan, Stuart A, Hassan-Smith, Zaki K, Doig, Craig L, Sherlock, Mark, Stewart, Paul M, Lavery, Gareth G
Published in J Endocrinol (2016)

11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice

by Doig, Craig L., Fletcher, Rachel S., Morgan, Stuart A., McCabe, Emma L., Larner, Dean P., Tomlinson, Jeremy W., Stewart, Paul M., Philp, Andrew, Lavery, Gareth G.
Published in Endocrinology (2017)

Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease

by Larner, Dean P., Morgan, Stuart A., Gathercole, Laura L., Doig, Craig L., Guest, Phil, Weston, Christopher, Hazeldine, Jon, Tomlinson, Jeremy W., Stewart, Paul M., Lavery, Gareth G.
Published in Endocrinology (2016)

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD (+) depletion

by Oakey, Lucy A., Fletcher, Rachel S., Elhassan, Yasir S., Cartwright, David M., Doig, Craig L., Garten, Antje, Thakker, Alpesh, Maddocks, Oliver D. K., Zhang, Tong, Tennant, Daniel A., Ludwig, Christian, Lavery, Gareth G.
Published in Wellcome Open Res (2019)

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

by Fine, Nicholas H.F., Doig, Craig L., Elhassan, Yasir S., Vierra, Nicholas C., Marchetti, Piero, Bugliani, Marco, Nano, Rita, Piemonti, Lorenzo, Rutter, Guy A., Jacobson, David A., Lavery, Gareth G., Hodson, David J.
Published in Diabetes (2018)

Epigenetic control of a VDR-governed feed-forward loop that regulates p21((waf1/cip1)) expression and function in non-malignant prostate cells

by Thorne, James L., Maguire, Orla, Doig, Craig L., Battaglia, Sebastiano, Fehr, Leah, Sucheston, Lara E., Heinaniemi, Merja, O’Neill, Laura P., McCabe, Christopher J., Turner, Bryan M., Carlberg, Carsten, Campbell, Moray J.
Published 2011

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

by Fletcher, Rachel S., Ratajczak, Joanna, Doig, Craig L., Oakey, Lucy A., Callingham, Rebecca, Da Silva Xavier, Gabriella, Garten, Antje, Elhassan, Yasir S., Redpath, Philip, Migaud, Marie E., Philp, Andrew, Brenner, Charles, Canto, Carles, Lavery, Gareth G.
Published in Mol Metab (2017)

Induction of the nicotinamide riboside kinase NAD(+) salvage pathway in a model of sarcoplasmic reticulum dysfunction

by Doig, Craig L., Zielinska, Agnieszka E., Fletcher, Rachel S., Oakey, Lucy A., Elhassan, Yasir S., Garten, Antje, Cartwright, David, Heising, Silke, Alsheri, Ahmed, Watson, David G., Prehn, Cornelia, Adamski, Jerzy, Tennant, Daniel A., Lavery, Gareth G.
Published in Skelet Muscle (2020)

Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns

by Doig, Craig L., Singh, Prashant K., Dhiman, Vineet K., Thorne, James L., Battaglia, Sebastiano, Sobolewski, Michelle, Maguire, Orla, O’Neill, Laura P., Turner, Bryan M., McCabe, Christopher J., Smiraglia, Dominic J., Campbell, Moray J.
Published 2013

11β‐Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation

by Hardy, Rowan S, Doig, Craig L, Hussain, Zahrah, O'Leary, Mary, Morgan, Stuart A, Pearson, Mark J, Naylor, Amy, Jones, Simon W, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Lavery, Gareth G, Cooper, Mark S, Raza, Karim
Published in J Pathol (2016)

Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion

by Battaglia, Sebastiano, Maguire, Orla, Thorne, James L., Hornung, Laura B., Doig, Craig L., Liu, Song, Sucheston, Lara E., Bianchi, Anna, Khanim, Farhat L., Gommersall, Lyndon M., Coulter, Henry S.O., Rakha, Serena, Giddings, Ian, O'Neill, Laura P., Cooper, Colin S., McCabe, Christopher J., Bunce, Christopher M., Campbell, Moray J.
Published 2010

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

by Elhassan, Yasir S., Kluckova, Katarina, Fletcher, Rachel S., Schmidt, Mark S., Garten, Antje, Doig, Craig L., Cartwright, David M., Oakey, Lucy, Burley, Claire V., Jenkinson, Ned, Wilson, Martin, Lucas, Samuel J.E., Akerman, Ildem, Seabright, Alex, Lai, Yu-Chiang, Tennant, Daniel A., Nightingale, Peter, Wallis, Gareth A., Manolopoulos, Konstantinos N., Brenner, Charles, Philp, Andrew, Lavery, Gareth G.
Published in Cell Rep (2019)