Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion

The loss of anti-proliferative responsiveness in prostate cancer cell lines toward ligands for vitamin D receptor, retinoic acid receptors/retinoid X receptors and peroxisome proliferator activated receptor (PPAR)α/γ may entail underlying epigenetic events, as ligand insensitivity reflects significa...

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Detalhes bibliográficos
Main Authors: Battaglia, Sebastiano, Maguire, Orla, Thorne, James L., Hornung, Laura B., Doig, Craig L., Liu, Song, Sucheston, Lara E., Bianchi, Anna, Khanim, Farhat L., Gommersall, Lyndon M., Coulter, Henry S.O., Rakha, Serena, Giddings, Ian, O'Neill, Laura P., Cooper, Colin S., McCabe, Christopher J., Bunce, Christopher M., Campbell, Moray J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930800/
https://ncbi.nlm.nih.gov/pubmed/20466759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq086
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