Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion

The loss of anti-proliferative responsiveness in prostate cancer cell lines toward ligands for vitamin D receptor, retinoic acid receptors/retinoid X receptors and peroxisome proliferator activated receptor (PPAR)α/γ may entail underlying epigenetic events, as ligand insensitivity reflects significa...

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Main Authors: Battaglia, Sebastiano, Maguire, Orla, Thorne, James L., Hornung, Laura B., Doig, Craig L., Liu, Song, Sucheston, Lara E., Bianchi, Anna, Khanim, Farhat L., Gommersall, Lyndon M., Coulter, Henry S.O., Rakha, Serena, Giddings, Ian, O'Neill, Laura P., Cooper, Colin S., McCabe, Christopher J., Bunce, Christopher M., Campbell, Moray J.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
主題:
Carcinogenesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930800/
https://ncbi.nlm.nih.gov/pubmed/20466759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq086
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