Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion

The loss of anti-proliferative responsiveness in prostate cancer cell lines toward ligands for vitamin D receptor, retinoic acid receptors/retinoid X receptors and peroxisome proliferator activated receptor (PPAR)α/γ may entail underlying epigenetic events, as ligand insensitivity reflects significa...

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Главные авторы: Battaglia, Sebastiano, Maguire, Orla, Thorne, James L., Hornung, Laura B., Doig, Craig L., Liu, Song, Sucheston, Lara E., Bianchi, Anna, Khanim, Farhat L., Gommersall, Lyndon M., Coulter, Henry S.O., Rakha, Serena, Giddings, Ian, O'Neill, Laura P., Cooper, Colin S., McCabe, Christopher J., Bunce, Christopher M., Campbell, Moray J.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Carcinogenesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930800/
https://ncbi.nlm.nih.gov/pubmed/20466759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq086
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