Epigenetic control of a VDR-governed feed-forward loop that regulates p21((waf1/cip1)) expression and function in non-malignant prostate cells

In non-malignant RWPE-1 prostate epithelial cells signaling by the nuclear receptor Vitamin D Receptor (VDR, NR1I1) induces cell cycle arrest through targets including CDKN1A (encodes p21((waf1/cip1))). VDR dynamically induced individual histone modification patterns at three VDR binding sites (R1,...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Thorne, James L., Maguire, Orla, Doig, Craig L., Battaglia, Sebastiano, Fehr, Leah, Sucheston, Lara E., Heinaniemi, Merja, O’Neill, Laura P., McCabe, Christopher J., Turner, Bryan M., Carlberg, Carsten, Campbell, Moray J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Gene Regulation, Chromatin and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064804/
https://ncbi.nlm.nih.gov/pubmed/21088000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq875
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires