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Regulation of the human p21((waf1/cip1)) gene promoter via multiple binding sites for p53 and the vitamin D(3) receptor

The main regulator of the human tumor suppresser gene p21((waf1/cip1)) is the transcription factor p53, but more recently it has been suggested to be a primary anti-proliferative target for the nuclear receptor VDR in the presence of its ligand 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)). To iden...

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Main Authors: Saramäki, Anna, Banwell, Claire M., Campbell, Moray J., Carlberg, Carsten
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351372/
https://ncbi.nlm.nih.gov/pubmed/16434701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj460
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