Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism

The adverse metabolic effects of prescribed and endogenous glucocorticoid excess, ‘Cushing’s syndrome’, create a significant health burden. While skeletal muscle atrophy and resultant myopathy is a clinical feature, the molecular mechanisms underpinning these changes are not fully defined. We have c...

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Bibliographic Details
Published in:J Endocrinol
Main Authors: Morgan, Stuart A, Hassan-Smith, Zaki K, Doig, Craig L, Sherlock, Mark, Stewart, Paul M, Lavery, Gareth G
Format: Artigo
Language:Inglês
Published: Bioscientifica Ltd 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064767/
https://ncbi.nlm.nih.gov/pubmed/27048233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0011
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