Cellular and genetic models of H6PDH and 11β‐HSD1 function in skeletal muscle

par Zielinska, Agnieszka E., Fletcher, Rachel S., Sherlock, Mark, Doig, Craig L., Lavery, Gareth G.
Publié dans Cell Biochem Funct (2017)

Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells

par Doig, Craig L., Battaglia, Sebastiano, Khanim, Farhat L., Bunce, Christopher M., Campbell, Moray J.
Publié dans J Steroid Biochem Mol Biol (2015)

TNFα-mediated Hsd11b1 binding of NF-κB p65 is associated with suppression of 11β-HSD1 in muscle

par Doig, Craig L, Bashir, Jamila, Zielinska, Agnieszka E, Cooper, Mark S, Stewart, Paul M, Lavery, Gareth G
Publié 2014

Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells

par Singh, Prashant K., Doig, Craig L., Dhiman, Vineet K., Turner, Bryan M., Smiraglia, Dominic J., Campbell, Moray J.
Publié dans J Steroid Biochem Mol Biol (2012)

Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism

par Morgan, Stuart A, Hassan-Smith, Zaki K, Doig, Craig L, Sherlock, Mark, Stewart, Paul M, Lavery, Gareth G
Publié dans J Endocrinol (2016)

11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice

par Doig, Craig L., Fletcher, Rachel S., Morgan, Stuart A., McCabe, Emma L., Larner, Dean P., Tomlinson, Jeremy W., Stewart, Paul M., Philp, Andrew, Lavery, Gareth G.
Publié dans Endocrinology (2017)

Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease

par Larner, Dean P., Morgan, Stuart A., Gathercole, Laura L., Doig, Craig L., Guest, Phil, Weston, Christopher, Hazeldine, Jon, Tomlinson, Jeremy W., Stewart, Paul M., Lavery, Gareth G.
Publié dans Endocrinology (2016)

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD (+) depletion

par Oakey, Lucy A., Fletcher, Rachel S., Elhassan, Yasir S., Cartwright, David M., Doig, Craig L., Garten, Antje, Thakker, Alpesh, Maddocks, Oliver D. K., Zhang, Tong, Tennant, Daniel A., Ludwig, Christian, Lavery, Gareth G.
Publié dans Wellcome Open Res (2019)

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

par Fine, Nicholas H.F., Doig, Craig L., Elhassan, Yasir S., Vierra, Nicholas C., Marchetti, Piero, Bugliani, Marco, Nano, Rita, Piemonti, Lorenzo, Rutter, Guy A., Jacobson, David A., Lavery, Gareth G., Hodson, David J.
Publié dans Diabetes (2018)

Epigenetic control of a VDR-governed feed-forward loop that regulates p21((waf1/cip1)) expression and function in non-malignant prostate cells

par Thorne, James L., Maguire, Orla, Doig, Craig L., Battaglia, Sebastiano, Fehr, Leah, Sucheston, Lara E., Heinaniemi, Merja, O’Neill, Laura P., McCabe, Christopher J., Turner, Bryan M., Carlberg, Carsten, Campbell, Moray J.
Publié 2011

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

par Fletcher, Rachel S., Ratajczak, Joanna, Doig, Craig L., Oakey, Lucy A., Callingham, Rebecca, Da Silva Xavier, Gabriella, Garten, Antje, Elhassan, Yasir S., Redpath, Philip, Migaud, Marie E., Philp, Andrew, Brenner, Charles, Canto, Carles, Lavery, Gareth G.
Publié dans Mol Metab (2017)

Induction of the nicotinamide riboside kinase NAD(+) salvage pathway in a model of sarcoplasmic reticulum dysfunction

par Doig, Craig L., Zielinska, Agnieszka E., Fletcher, Rachel S., Oakey, Lucy A., Elhassan, Yasir S., Garten, Antje, Cartwright, David, Heising, Silke, Alsheri, Ahmed, Watson, David G., Prehn, Cornelia, Adamski, Jerzy, Tennant, Daniel A., Lavery, Gareth G.
Publié dans Skelet Muscle (2020)

Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns

par Doig, Craig L., Singh, Prashant K., Dhiman, Vineet K., Thorne, James L., Battaglia, Sebastiano, Sobolewski, Michelle, Maguire, Orla, O’Neill, Laura P., Turner, Bryan M., McCabe, Christopher J., Smiraglia, Dominic J., Campbell, Moray J.
Publié 2013

11β‐Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation

par Hardy, Rowan S, Doig, Craig L, Hussain, Zahrah, O'Leary, Mary, Morgan, Stuart A, Pearson, Mark J, Naylor, Amy, Jones, Simon W, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Lavery, Gareth G, Cooper, Mark S, Raza, Karim
Publié dans J Pathol (2016)

Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion

par Battaglia, Sebastiano, Maguire, Orla, Thorne, James L., Hornung, Laura B., Doig, Craig L., Liu, Song, Sucheston, Lara E., Bianchi, Anna, Khanim, Farhat L., Gommersall, Lyndon M., Coulter, Henry S.O., Rakha, Serena, Giddings, Ian, O'Neill, Laura P., Cooper, Colin S., McCabe, Christopher J., Bunce, Christopher M., Campbell, Moray J.
Publié 2010

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

par Elhassan, Yasir S., Kluckova, Katarina, Fletcher, Rachel S., Schmidt, Mark S., Garten, Antje, Doig, Craig L., Cartwright, David M., Oakey, Lucy, Burley, Claire V., Jenkinson, Ned, Wilson, Martin, Lucas, Samuel J.E., Akerman, Ildem, Seabright, Alex, Lai, Yu-Chiang, Tennant, Daniel A., Nightingale, Peter, Wallis, Gareth A., Manolopoulos, Konstantinos N., Brenner, Charles, Philp, Andrew, Lavery, Gareth G.
Publié dans Cell Rep (2019)