Cellular and genetic models of H6PDH and 11β‐HSD1 function in skeletal muscle

Autor Zielinska, Agnieszka E., Fletcher, Rachel S., Sherlock, Mark, Doig, Craig L., Lavery, Gareth G.
Vydáno v Cell Biochem Funct (2017)

Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells

Autor Doig, Craig L., Battaglia, Sebastiano, Khanim, Farhat L., Bunce, Christopher M., Campbell, Moray J.
Vydáno v J Steroid Biochem Mol Biol (2015)

TNFα-mediated Hsd11b1 binding of NF-κB p65 is associated with suppression of 11β-HSD1 in muscle

Autor Doig, Craig L, Bashir, Jamila, Zielinska, Agnieszka E, Cooper, Mark S, Stewart, Paul M, Lavery, Gareth G
Vydáno 2014

Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells

Autor Singh, Prashant K., Doig, Craig L., Dhiman, Vineet K., Turner, Bryan M., Smiraglia, Dominic J., Campbell, Moray J.
Vydáno v J Steroid Biochem Mol Biol (2012)

Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism

Autor Morgan, Stuart A, Hassan-Smith, Zaki K, Doig, Craig L, Sherlock, Mark, Stewart, Paul M, Lavery, Gareth G
Vydáno v J Endocrinol (2016)

11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice

Autor Doig, Craig L., Fletcher, Rachel S., Morgan, Stuart A., McCabe, Emma L., Larner, Dean P., Tomlinson, Jeremy W., Stewart, Paul M., Philp, Andrew, Lavery, Gareth G.
Vydáno v Endocrinology (2017)

Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease

Autor Larner, Dean P., Morgan, Stuart A., Gathercole, Laura L., Doig, Craig L., Guest, Phil, Weston, Christopher, Hazeldine, Jon, Tomlinson, Jeremy W., Stewart, Paul M., Lavery, Gareth G.
Vydáno v Endocrinology (2016)

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD (+) depletion

Autor Oakey, Lucy A., Fletcher, Rachel S., Elhassan, Yasir S., Cartwright, David M., Doig, Craig L., Garten, Antje, Thakker, Alpesh, Maddocks, Oliver D. K., Zhang, Tong, Tennant, Daniel A., Ludwig, Christian, Lavery, Gareth G.
Vydáno v Wellcome Open Res (2019)

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Autor Fine, Nicholas H.F., Doig, Craig L., Elhassan, Yasir S., Vierra, Nicholas C., Marchetti, Piero, Bugliani, Marco, Nano, Rita, Piemonti, Lorenzo, Rutter, Guy A., Jacobson, David A., Lavery, Gareth G., Hodson, David J.
Vydáno v Diabetes (2018)

Epigenetic control of a VDR-governed feed-forward loop that regulates p21((waf1/cip1)) expression and function in non-malignant prostate cells

Autor Thorne, James L., Maguire, Orla, Doig, Craig L., Battaglia, Sebastiano, Fehr, Leah, Sucheston, Lara E., Heinaniemi, Merja, O’Neill, Laura P., McCabe, Christopher J., Turner, Bryan M., Carlberg, Carsten, Campbell, Moray J.
Vydáno 2011

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

Autor Fletcher, Rachel S., Ratajczak, Joanna, Doig, Craig L., Oakey, Lucy A., Callingham, Rebecca, Da Silva Xavier, Gabriella, Garten, Antje, Elhassan, Yasir S., Redpath, Philip, Migaud, Marie E., Philp, Andrew, Brenner, Charles, Canto, Carles, Lavery, Gareth G.
Vydáno v Mol Metab (2017)

Induction of the nicotinamide riboside kinase NAD(+) salvage pathway in a model of sarcoplasmic reticulum dysfunction

Autor Doig, Craig L., Zielinska, Agnieszka E., Fletcher, Rachel S., Oakey, Lucy A., Elhassan, Yasir S., Garten, Antje, Cartwright, David, Heising, Silke, Alsheri, Ahmed, Watson, David G., Prehn, Cornelia, Adamski, Jerzy, Tennant, Daniel A., Lavery, Gareth G.
Vydáno v Skelet Muscle (2020)

Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns

Autor Doig, Craig L., Singh, Prashant K., Dhiman, Vineet K., Thorne, James L., Battaglia, Sebastiano, Sobolewski, Michelle, Maguire, Orla, O’Neill, Laura P., Turner, Bryan M., McCabe, Christopher J., Smiraglia, Dominic J., Campbell, Moray J.
Vydáno 2013

11β‐Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation

Autor Hardy, Rowan S, Doig, Craig L, Hussain, Zahrah, O'Leary, Mary, Morgan, Stuart A, Pearson, Mark J, Naylor, Amy, Jones, Simon W, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Lavery, Gareth G, Cooper, Mark S, Raza, Karim
Vydáno v J Pathol (2016)

Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion

Autor Battaglia, Sebastiano, Maguire, Orla, Thorne, James L., Hornung, Laura B., Doig, Craig L., Liu, Song, Sucheston, Lara E., Bianchi, Anna, Khanim, Farhat L., Gommersall, Lyndon M., Coulter, Henry S.O., Rakha, Serena, Giddings, Ian, O'Neill, Laura P., Cooper, Colin S., McCabe, Christopher J., Bunce, Christopher M., Campbell, Moray J.
Vydáno 2010

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

Autor Elhassan, Yasir S., Kluckova, Katarina, Fletcher, Rachel S., Schmidt, Mark S., Garten, Antje, Doig, Craig L., Cartwright, David M., Oakey, Lucy, Burley, Claire V., Jenkinson, Ned, Wilson, Martin, Lucas, Samuel J.E., Akerman, Ildem, Seabright, Alex, Lai, Yu-Chiang, Tennant, Daniel A., Nightingale, Peter, Wallis, Gareth A., Manolopoulos, Konstantinos N., Brenner, Charles, Philp, Andrew, Lavery, Gareth G.
Vydáno v Cell Rep (2019)