p53 Hypersensitivity Is the Predominant Mechanism of the Unique Responsiveness of Testicular Germ Cell Tumor (TGCT) Cells to Cisplatin

מאת Gutekunst, Matthias, Oren, Moshe, Weilbacher, Andrea, Dengler, Michael A., Markwardt, Christiane, Thomale, Jürgen, Aulitzky, Walter E., van der Kuip, Heiko
יצא לאור 2011

Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target

מאת Iyer, Sweta, Uren, Rachel T., Dengler, Michael A., Shi, Melissa X., Uno, Etsuko, Adams, Jerry M., Dewson, Grant, Kluck, Ruth M.
הוצא לאור ב Cell Death Dis (2020)

Oncogenic Stress Induced by Acute Hyper-Activation of Bcr-Abl Leads to Cell Death upon Induction of Excessive Aerobic Glycolysis

מאת Dengler, Michael A., Staiger, Annette M., Gutekunst, Matthias, Hofmann, Ute, Doszczak, Malgorzata, Scheurich, Peter, Schwab, Matthias, Aulitzky, Walter E., van der Kuip, Heiko
יצא לאור 2011

BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove

מאת Li, Mark Xiang, Tan, Iris K. L., Ma, Stephen B., Hockings, Colin, Kratina, Tobias, Dengler, Michael A., Alsop, Amber E., Kluck, Ruth M., Dewson, Grant
הוצא לאור ב Proc Natl Acad Sci U S A (2017)

Characterization of a novel human BFL-1-specific monoclonal antibody

מאת Gangoda, Lahiru, Teh, Charis E., Dengler, Michael A., Best, Sarah A., Weeden, Clare E., Tai, Lin, Lee, Erinna F., Fairlie, Walter D., Sutherland, Kate D., Harrison, Leonard C., Gray, Daniel H., Strasser, Andreas, Herold, Marco J.
הוצא לאור ב Cell Death Differ (2019)

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

מאת Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.
הוצא לאור ב Immunity (2020)

Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice

מאת Pymm, Phillip, Adair, Amy, Chan, Li-Jin, Cooney, James P., Mordant, Francesca L., Allison, Cody C., Lopez, Ester, Haycroft, Ebene R., O’Neill, Matthew T., Tan, Li Lynn, Dietrich, Melanie H., Drew, Damien, Doerflinger, Marcel, Dengler, Michael A., Scott, Nichollas E., Wheatley, Adam K., Gherardin, Nicholas A., Venugopal, Hariprasad, Cromer, Deborah, Davenport, Miles P., Pickering, Raelene, Godfrey, Dale I., Purcell, Damian F. J., Kent, Stephen J., Chung, Amy W., Subbarao, Kanta, Pellegrini, Marc, Glukhova, Alisa, Tham, Wai-Hong
הוצא לאור ב Proc Natl Acad Sci U S A (2021)

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

מאת Thijssen, Rachel, Diepstraten, Sarah T., Moujalled, Donia, Chew, Edward, Flensburg, Christoffer, Shi, Melissa X., Dengler, Michael A., Litalien, Veronique, MacRaild, Sarah, Chen, Maoshan, Anstee, Natasha S., Reljić, Boris, Gabriel, Sarah S., Djajawi, Tirta M., Riffkin, Chris D., Aubrey, Brandon J., Chang, Catherine, Tai, Lin, Xu, Zhen, Morley, Thomas, Pomilio, Giovanna, Bruedigam, Claudia, Kallies, Axel, Stroud, David A., Bajel, Ashish, Kluck, Ruth M., Lane, Steven W., Schoumacher, Marie, Banquet, Sébastien, Majewski, Ian J., Strasser, Andreas, Roberts, Andrew W., Huang, David C. S., Brown, Fiona C., Kelly, Gemma L., Wei, Andrew H.
הוצא לאור ב Blood (2021)