Adduct-specific monoclonal antibodies for the measurement of cisplatin-induced DNA lesions in individual cell nuclei

Por Liedert, Bernd, Pluim, Dick, Schellens, Jan, Thomale, Jürgen
Publicado em 2006

Fast repair of O(6)-ethylguanine, but not O(6)-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of m...

Por Engelbergs, Jörg, Thomale, Jürgen, Galhoff, Anke, Rajewsky, Manfred F.
Publicado em 1998

Drug resistance and DNA repair in leukaemia

Por Müller, Mark R., Thomale, Jürgen, Rajewsky, Manfred F., Seeber, Siegfried
Publicado em 1998

Targeted Single Wall Carbon Nanotube Mediated Pt(IV) Prodrug Delivery Using Folate as a Homing Device

Por Dhar, Shanta, Liu, Zhuang, Thomale, Jürgen, Dai, Hongjie, Lippard, Stephen J.
Publicado em 2008

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation

Por Keitel, Ulrike, Scheel, Andreas, Thomale, Jürgen, Halpape, Rovena, Kaulfuß, Silke, Scheel, Christina, Dobbelstein, Matthias
Publicado no Oncotarget (2014)

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression

Por Usanova, Svetlana, Piée-Staffa, Andrea, Sied, Ulrike, Thomale, Jürgen, Schneider, Astrid, Kaina, Bernd, Köberle, Beate
Publicado em 2010

FTO levels affect RNA modification and the transcriptome

Por Berulava, Tea, Ziehe, Matthias, Klein-Hitpass, Ludger, Mladenov, Emil, Thomale, Jürgen, Rüther, Ulrich, Horsthemke, Bernhard
Publicado em 2013

Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells

Por Wang, Qi-En, Milum, Keisha, Han, Chunhua, Huang, Yi-Wen, Wani, Gulzar, Thomale, Jürgen, Wani, Altaf A
Publicado em 2011

p53 Hypersensitivity Is the Predominant Mechanism of the Unique Responsiveness of Testicular Germ Cell Tumor (TGCT) Cells to Cisplatin

Por Gutekunst, Matthias, Oren, Moshe, Weilbacher, Andrea, Dengler, Michael A., Markwardt, Christiane, Thomale, Jürgen, Aulitzky, Walter E., van der Kuip, Heiko
Publicado em 2011

DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression

Por Hampp, Stephanie, Kiessling, Tina, Buechle, Kerstin, Mansilla, Sabrina F., Thomale, Jürgen, Rall, Melanie, Ahn, Jinwoo, Pospiech, Helmut, Gottifredi, Vanesa, Wiesmüller, Lisa
Publicado no Proc Natl Acad Sci U S A (2016)

ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinoma

Por Bretz, Anne Catherine, Gittler, Miriam P., Charles, Joël P., Gremke, Niklas, Eckhardt, Ines, Mernberger, Marco, Mandic, Robert, Thomale, Jürgen, Nist, Andrea, Wanzel, Michael, Stiewe, Thorsten
Publicado no Nucleic Acids Res (2016)

Reciprocal Relationship between O(6)-Methylguanine-DNA Methyltransferase P140K Expression Level and Chemoprotection of Hematopoietic Stem Cells

Por Milsom, Michael D., Jerabek-Willemsen, Moran, Harris, Chad E., Schambach, Axel, Broun, Emily, Bailey, Jeff, Jansen, Michael, Schleimer, David, Nattamai, Kalpana, Wilhelm, Jamie, Watson, Amanda, Geiger, Hartmut, Margison, Geoffrey P., Moritz, Thomas, Baum, Christopher, Thomale, Jürgen, Williams, David A.
Publicado no Cancer Res (2008)

ERCC1 Isoform Expression and DNA Repair in Non–Small-Cell Lung Cancer

Por Friboulet, Luc, Olaussen, Ken André, Pignon, Jean-Pierre, Shepherd, Frances A., Tsao, Ming-Sound, Graziano, Stephen, Kratzke, Robert, Douillard, Jean-Yves, Seymour, Lesley, Pirker, Robert, Filipits, Martin, André, Fabrice, Solary, Eric, Ponsonnailles, Florence, Robin, Angélique, Stoclin, Annabelle, Dorvault, Nicolas, Commo, Frédéric, Adam, Julien, Vanhecke, Elsa, Saulnier, Patrick, Thomale, Jürgen, Le Chevalier, Thierry, Dunant, Ariane, Rousseau, Vanessa, Le Teuff, Gwénaël, Brambilla, Elisabeth, Soria, Jean-Charles
Publicado em 2013