Feedback Regulation of Cholesterol Synthesis: Sterol-Accelerated Ubiquitination and Degradation of HMG CoA Reductase

por DeBose-Boyd, Russell A.
Publicado 2008

Control of Cholesterol Synthesis through Regulated ER-Associated Degradation of HMG CoA Reductase

por Jo, Youngah, DeBose-Boyd, Russell A.
Publicado 2010

Regulation of Cholesterol and Fatty Acid Synthesis

por Ye, Jin, DeBose-Boyd, Russell A.
Publicado 2011

SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond

por DeBose-Boyd, Russell A., Ye, Jin
Publicado en Trends Biochem Sci (2018)

Opening up new fronts in the fight against cholesterol

por DeBose-Boyd, Russell A, Horton, Jay D
Publicado 2013

Underlying Mechanisms for Sterol-Induced Ubiquitination and ER-Associated Degradation of HMG CoA Reductase

por Johnson, Brittany M., DeBose-Boyd, Russell A.
Publicado en Semin Cell Dev Biol (2017)

Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells

por Lee, Peter C. W., DeBose-Boyd, Russell A.
Publicado 2010

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

por Jo, Youngah, Sguigna, Peter V., DeBose-Boyd, Russell A.
Publicado 2011

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet–associated endoplasmic reticulum membranes

por Jo, Youngah, Hartman, Isamu Z., DeBose-Boyd, Russell A.
Publicado 2013

Insig-mediated, Sterol-accelerated Degradation of the Membrane Domain of Hamster 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase in Insect Cells

por Nguyen, Andrew D., Lee, Soo Hee, DeBose-Boyd, Russell A.
Publicado 2009

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells

por Elsabrouty, Rania, Jo, Youngah, Dinh, Tammy T., DeBose-Boyd, Russell A.
Publicado 2013

Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands

por DeBose-Boyd, Russell A., Ou, Jiafu, Goldstein, Joseph L., Brown, Michael S.
Publicado 2001

Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells

por Faulkner, Rebecca A., Nguyen, Andrew D., Jo, Youngah, DeBose-Boyd, Russell A.
Publicado 2013

Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi

por Nohturfft, Axel, DeBose-Boyd, Russell A., Scheek, Sigrid, Goldstein, Joseph L., Brown, Michael S.
Publicado 1999

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

por Jo, Youngah, Lee, Peter C. W., Sguigna, Peter V., DeBose-Boyd, Russell A.
Publicado 2011

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

por Schumacher, Marc M, Elsabrouty, Rania, Seemann, Joachim, Jo, Youngah, DeBose-Boyd, Russell A
Publicado en eLife (2015)

UbiA prenyltransferase domain–containing protein-1 modulates HMG-CoA reductase degradation to coordinate synthesis of sterol and nonsterol isoprenoids

por Schumacher, Marc M., Jun, Dong-Jae, Johnson, Brittany M., DeBose-Boyd, Russell A.
Publicado en J Biol Chem (2018)

Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi

por Schumacher, Marc M., Jun, Dong-Jae, Jo, Youngah, Seemann, Joachim, DeBose-Boyd, Russell A.
Publicado en J Lipid Res (2016)

Sequential Actions of the AAA-ATPase Valosin-containing Protein (VCP)/p97 and the Proteasome 19 S Regulatory Particle in Sterol-accelerated, Endoplasmic Reticulum (ER)-associated D...

por Morris, Lindsey L., Hartman, Isamu Z., Jun, Dong-Jae, Seemann, Joachim, DeBose-Boyd, Russell A.
Publicado 2014

Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver

por Hwang, Seonghwan, Nguyen, Andrew D., Jo, Youngah, Engelking, Luke J., Brugarolas, James, DeBose-Boyd, Russell A.
Publicado en J Biol Chem (2017)