Asymmetric conformational changes in a GPCR dimer controlled by G-proteins

Por Damian, Marjorie, Martin, Aimée, Mesnier, Danielle, Pin, Jean-Philippe, Banères, Jean-Louis
Publicado em 2006

G Protein Activation by the Leukotriene B(4) Receptor Dimer: EVIDENCE FOR AN ABSENCE OF TRANS-ACTIVATION

Por Damian, Marjorie, Mary, Sophie, Martin, Aimée, Pin, Jean-Philippe, Banères, Jean-Louis
Publicado em 2008

Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor

Por Mary, Sophie, Damian, Marjorie, Louet, Maxime, Floquet, Nicolas, Fehrentz, Jean-Alain, Marie, Jacky, Martinez, Jean, Banères, Jean-Louis
Publicado em 2012

Engineering a G protein-coupled receptor for structural studies: Stabilization of the BLT1 receptor ground state

Por Martin, Aimée, Damian, Marjorie, Laguerre, Michel, Parello, Joseph, Pucci, Bernard, Serre, Laurence, Mary, Sophie, Marie, Jacky, Banères, Jean-Louis
Publicado em 2009

High Constitutive Activity Is an Intrinsic Feature of Ghrelin Receptor Protein: A STUDY WITH A FUNCTIONAL MONOMERIC GHS-R1a RECEPTOR RECONSTITUTED IN LIPID DISCS

Por Damian, Marjorie, Marie, Jacky, Leyris, Jean-Philippe, Fehrentz, Jean-Alain, Verdié, Pascal, Martinez, Jean, Banères, Jean-Louis, Mary, Sophie
Publicado em 2012

Heterodimerization with Its Splice Variant Blocks the Ghrelin Receptor 1a in a Non-signaling Conformation: A STUDY WITH A PURIFIED HETERODIMER ASSEMBLED INTO LIPID DISCS

Por Mary, Sophie, Fehrentz, Jean-Alain, Damian, Marjorie, Gaibelet, Gérald, Orcel, Hélène, Verdié, Pascal, Mouillac, Bernard, Martinez, Jean, Marie, Jacky, Banères, Jean-Louis
Publicado em 2013

Inhibition of Heterotrimeric G Protein Signaling by a Small Molecule Acting on Gα Subunit

Por Ayoub, Mohammed Akli, Damian, Marjorie, Gespach, Christian, Ferrandis, Eric, Lavergne, Olivier, De Wever, Olivier, Banères, Jean-Louis, Pin, Jean-Philippe, Prévost, Grégoire Pierre
Publicado em 2009

Structure of the agonist 12–HHT in its BLT2 receptor-bound state

Por Giusti, Fabrice, Casiraghi, Marina, Point, Elodie, Damian, Marjorie, Rieger, Jutta, Bon, Christel Le, Pozza, Alexandre, Moncoq, Karine, Banères, Jean-Louis, Catoire, Laurent J.
Publicado no Sci Rep (2020)

Leukotriene BLT2 Receptor Monomers Activate the G(i2) GTP-binding Protein More Efficiently than Dimers

Por Arcemisbéhère, Laure, Sen, Tuhinadri, Boudier, Laure, Balestre, Marie-Noëlle, Gaibelet, Gérald, Detouillon, Emilie, Orcel, Hélène, Mendre, Christiane, Rahmeh, Rita, Granier, Sébastien, Vivès, Corinne, Fieschi, Franck, Damian, Marjorie, Durroux, Thierry, Banères, Jean-Louis, Mouillac, Bernard
Publicado em 2010

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling

Por M'Kadmi, Céline, Leyris, Jean-Philippe, Onfroy, Lauriane, Galés, Céline, Saulière, Aude, Gagne, Didier, Damian, Marjorie, Mary, Sophie, Maingot, Mathieu, Denoyelle, Séverine, Verdié, Pascal, Fehrentz, Jean-Alain, Martinez, Jean, Banères, Jean-Louis, Marie, Jacky
Publicado no J Biol Chem (2015)

Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy

Por Rahmeh, Rita, Damian, Marjorie, Cottet, Martin, Orcel, Hélène, Mendre, Christiane, Durroux, Thierry, Sharma, K. Shivaji, Durand, Grégory, Pucci, Bernard, Trinquet, Eric, Zwier, Jurriaan M., Deupi, Xavier, Bron, Patrick, Banères, Jean-Louis, Mouillac, Bernard, Granier, Sébastien
Publicado em 2012

Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain

Por Ferré, Guillaume, Louet, Maxime, Saurel, Oliver, Delort, Bartholomé, Czaplicki, Georges, M’Kadmi, Céline, Damian, Marjorie, Renault, Pedro, Cantel, Sonia, Gavara, Laurent, Demange, Pascal, Marie, Jacky, Fehrentz, Jean-Alain, Floquet, Nicolas, Milon, Alain, Banères, Jean-Louis
Publicado no Proc Natl Acad Sci U S A (2019)

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

Por Damian, Marjorie, Mary, Sophie, Maingot, Mathieu, M'Kadmi, Céline, Gagne, Didier, Leyris, Jean-Philippe, Denoyelle, Séverine, Gaibelet, Gérald, Gavara, Laurent, Garcia de Souza Costa, Mauricio, Perahia, David, Trinquet, Eric, Mouillac, Bernard, Galandrin, Ségolène, Galès, Céline, Fehrentz, Jean-Alain, Floquet, Nicolas, Martinez, Jean, Marie, Jacky, Banères, Jean-Louis
Publicado no Proc Natl Acad Sci U S A (2015)

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

Por Damian, Marjorie, Pons, Véronique, Renault, Pedro, M’Kadmi, Céline, Delort, Bartholomé, Hartmann, Lucie, Kaya, Ali I., Louet, Maxime, Gagne, Didier, Ben Haj Salah, Khoubaib, Denoyelle, Séverine, Ferry, Gilles, Boutin, Jean A., Wagner, Renaud, Fehrentz, Jean-Alain, Martinez, Jean, Marie, Jacky, Floquet, Nicolas, Galès, Céline, Mary, Sophie, Hamm, Heidi E., Banères, Jean-Louis
Publicado no Proc Natl Acad Sci U S A (2018)