Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy

G protein-coupled receptors (GPCRs) are seven-transmembrane proteins that mediate most cellular responses to hormones and neurotransmitters, representing the largest group of therapeutic targets. Recent studies show that some GPCRs signal through both G protein and arrestin pathways in a ligand-spec...

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Detalhes bibliográficos
Main Authors: Rahmeh, Rita, Damian, Marjorie, Cottet, Martin, Orcel, Hélène, Mendre, Christiane, Durroux, Thierry, Sharma, K. Shivaji, Durand, Grégory, Pucci, Bernard, Trinquet, Eric, Zwier, Jurriaan M., Deupi, Xavier, Bron, Patrick, Banères, Jean-Louis, Mouillac, Bernard, Granier, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340029/
https://ncbi.nlm.nih.gov/pubmed/22493271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201093109
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