Leukotriene BLT2 Receptor Monomers Activate the G(i2) GTP-binding Protein More Efficiently than Dimers

Accumulating evidence indicates that G protein-coupled receptors can assemble as dimers/oligomers but the role of this phenomenon in G protein coupling and signaling is not yet clear. We have used the purified leukotriene B(4) receptor BLT2 as a model to investigate the capacity of receptor monomers...

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Autores principales: Arcemisbéhère, Laure, Sen, Tuhinadri, Boudier, Laure, Balestre, Marie-Noëlle, Gaibelet, Gérald, Detouillon, Emilie, Orcel, Hélène, Mendre, Christiane, Rahmeh, Rita, Granier, Sébastien, Vivès, Corinne, Fieschi, Franck, Damian, Marjorie, Durroux, Thierry, Banères, Jean-Louis, Mouillac, Bernard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825429/
https://ncbi.nlm.nih.gov/pubmed/20026606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.083477
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