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Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening

The identification of new drugs exhibiting reduced adverse side-effects constitutes a great challenge for the next decade. Various steps are needed to screen for good ligand candidates and one of them is the evaluation of their binding properties. New strategies based on fluorescence measurement con...

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Main Authors: Cottet, Martin, Faklaris, Orestis, Zwier, Jurriaan M., Trinquet, Eric, Pin, Jean-Philippe, Durroux, Thierry
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052550/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph4010202
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