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Asymmetric conformational changes in a GPCR dimer controlled by G-proteins
G-protein-coupled receptors (GPCRs) are key players in cell communication. Although long considered as monomeric, it now appears that these heptahelical proteins can form homo- or heterodimers. Here, we analyzed the conformational changes in each subunit of a receptor dimer resulting from agonist bi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698895/ https://ncbi.nlm.nih.gov/pubmed/17139258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601449 |
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