AUGMENTED OXYGEN-MEDIATED TRANSCRIPIONAL ACTIVATION OF CYTOCHROME P450 (CYP)1A EXPRESSION AND INCREASED SUSCEPTIBILITIES TO HYPEROXIC LUNG INJURY IN TRANSGENIC MICE CARRYING THE HU...

Por JIANG, WEIWU, COUROUCLI, XANTHI I., WANG, LIHUA, BARRIOS, ROBERTO, MOORTHY, BHAGAVATULA
Publicado em 2011

Omeprazole Attenuates Hyperoxic Lung Injury in Mice via Aryl Hydrocarbon Receptor Activation and Is Associated with Increased Expression of Cytochrome P4501A Enzymes

Por Shivanna, Binoy, Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi I., Moorthy, Bhagavatula
Publicado em 2011

Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro

Por Tiwari, Kirti Kumar, Chu, Chun, Couroucli, Xanthi, Moorthy, Bhagavatula, Lingappan, Krithika
Publicado em 2014

Sex-specific differences in hyperoxic lung injury in mice: role of Cytochrome P450 (CYP)1A

Por Lingappan, Krithika, Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi I., Moorthy, Bhagavatula
Publicado no Toxicology (2015)

Analysis of the Transcriptome in Hyperoxic Lung Injury and Sex-Specific Alterations in Gene Expression

Por Lingappan, Krithika, Srinivasan, Chandra, Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi I., Moorthy, Bhagavatula
Publicado em 2014

Sex-specific Differences in Hyperoxic Lung Injury in Mice: Implications for Acute and Chronic Lung Disease in Humans

Por Lingappan, Krithika, Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi I., Barrios, Roberto, Moorthy, Bhagavatula
Publicado em 2013

Hyperoxia-mediated transcriptional activation of cytochrome P4501A1 (CYP1A1) and decreased susceptibility to oxygen-mediated lung injury in newborn mice

Por Jiang, Weiwu, Maturu, Paramahamsa, Liang, Yanhong Wei, Wang, Lihua, Lingappan, Krithika, Couroucli, Xanthi
Publicado no Biochem Biophys Res Commun (2017)

Regulation of Cytochrome P450-1A1 Expression by Hyperoxia in Human Lung Cell Lines: Implications for Hyperoxic Lung Injury

Por Bhakta, Kushal Y., Jiang, Weiwu, Couroucli, Xanthi I., Fazili, Inayat S., Muthiah, Kathirvel, Moorthy, Bhagavatula
Publicado em 2008

Functional Deficiency of Aryl Hydrocarbon Receptor Augments Oxygen Toxicity-Induced Alveolar Simplification in Newborn Mice

Por Shivanna, Binoy, Zhang, Wenyan, Jiang, Weiwu, Welty, Stephen E., Couroucli, Xanthi I., Wang, Lihua, Moorthy, Bhagavatula
Publicado em 2013

β-Naphthoflavone treatment attenuates neonatal hyperoxic lung injury in wild type Cyp1a2-knockout mice

Por Lingappan, Krithika, Maturu, Paramahamsa, Liang, Yanhong Wei, Jiang, Weiwu, Wang, Lihua, Moorthy, Bhagavatula, Couroucli, Xanthi I.
Publicado no Toxicol Appl Pharmacol (2017)

Disruption of the Gene for CYP1A2, which Is Expressed Primarily in Liver, Leads to Differential Regulation of Hepatic and Pulmonary Mouse CYP1A1 Expression and Augmented Human CYP1...

Por Jiang, Weiwu, Wang, Lihua, Kondraganti, Sudha R., Fazili, Inayat S., Couroucli, Xanthi I., Felix, Edward A., Moorthy, Bhagavatula
Publicado em 2010

PRENATAL ADMINISTRATION OF THE CYTOCHROME P4501A INDUCER, B-NAPHTHOFLAVONE (BNF), ATTENUATES HYPEROXIC LUNG INJURY IN NEWBORN MICE: IMPLICATIONS FOR BRONCHOPULMONARY DYSPLASIA (BPD...

Por Couroucli, Xanthi I., Liang, Yan-hong Wei, Jiang, Weiwu, Wang, Lihua, Barrios, Roberto, Yang, Peiying, Moorthy, Bhagavatula
Publicado em 2011

Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: a novel target for prevention of hyperoxic lung injury

Por Dinu, Daniela, Chu, Chun, Veith, Alex, Lingappan, Krithika, Couroucli, Xanthi, Jefcoate, Colin R., Sheibani, Nader, Moorthy, Bhagavatula
Publicado no Biochem Biophys Res Commun (2016)

Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome

Por Lingappan, Krithika, Maity, Suman, Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi, Veith, Alex, Zhou, Guodong, Coarfa, Cristian, Moorthy, Bhagavatula
Publicado no Sci Rep (2017)

Sexual dimorphism of the pulmonary transcriptome in neonatal hyperoxic lung injury: identification of angiogenesis as a key pathway

Por Coarfa, Cristian, Zhang, Yuhao, Maity, Suman, Perera, Dimuthu N., Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi, Moorthy, Bhagavatula, Lingappan, Krithika
Publicado no Am J Physiol Lung Cell Mol Physiol (2017)

Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal β-Naphthoflavone Administration: Implications for Broncho...

Por Maturu, Paramahamsa, Wei-Liang, Yanhong, Jiang, Weiwu, Wang, Lihua, Lingappan, Krithika, Barrios, Roberto, Liang, Yao, Moorthy, Bhagavatula, Couroucli, Xanthi I.
Publicado no Toxicol Sci (2017)

Effects of Dietary Fish Oil on the Depletion of Carcinogenic PAH-DNA Adduct Levels in the Liver of B6C3F1 Mouse

Por Zhou, Guo-Dong, Zhu, Huiping, Phillips, Tracie D., Wang, Jianbo, Wang, Shi-Zhou, Wang, Fen, Amendt, Brad A., Couroucli, Xanthi I., Donnelly, Kirby C., Moorthy, Bhagavatula
Publicado em 2011

Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene

Por Thakur, Vijay S., Liang, Yanhong W., Lingappan, Krithika, Jiang, Weiwu, Wang, Lihua, Barrios, Roberto, Zhou, Guodong, Guntupalli, Bharath, Shivanna, Binoy, Maturu, Paramahamsa, Welty, Stephen E., Moorthy, Bhagavatula, Couroucli, Xanthi I.
Publicado em 2014

Mice Deficient in the Gene for Cytochrome P450 (CYP)1A1 Are More Susceptible Than Wild-Type to Hyperoxic Lung Injury: Evidence for Protective Role of CYP1A1 Against Oxidative Stres...

Por Lingappan, Krithika, Jiang, Weiwu, Wang, Lihua, Wang, Gangduo, Couroucli, Xanthi I., Shivanna, Binoy, Welty, Stephen E., Barrios, Roberto, Khan,  M. Firoze, Nebert, Daniel W., Roberts, L. Jackson, Moorthy, Bhagavatula
Publicado em 2014

Disruption of Cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury

Por Wang, Lihua, Lingappan, Krithika, Jiang, Weiwu, Couroucli, Xanthi I., Welty, Stephen E., Shivanna, Binoy, Barrios, Roberto, Wang, Gangduo, Khan, M. Firoze, Gonzalez, Frank J., Roberts, L Jackson, Moorthy, Bhagavatula
Publicado no Free Radic Biol Med (2015)