Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome

Hyperoxia contributes to lung injury in experimental animals and diseases such as acute respiratory distress syndrome in humans. Cytochrome P450 (CYP)1A enzymes are protective against hyperoxic lung injury (HLI). The molecular pathways and differences in gene expression that modulate these protectiv...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lingappan, Krithika, Maity, Suman, Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi, Veith, Alex, Zhou, Guodong, Coarfa, Cristian, Moorthy, Bhagavatula
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428698/
https://ncbi.nlm.nih.gov/pubmed/28377578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00516-x
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