Mice Lacking the Cytochrome P450 1B1 Gene Are Less Susceptible to Hyperoxic Lung Injury Than Wild Type

Supplemental oxygen is a life-saving intervention administered to individuals suffering from respiratory distress, including adults with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Despite the clinical benefit, supplemental oxygen can create a hyperoxic environment that i...

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Bibliographic Details
Published in:Toxicol Sci
Main Authors: Veith, Alex C, Bou Aram, Boura’a, Jiang, Weiwu, Wang, Lihua, Zhou, Guodong, Jefcoate, Colin R, Couroucli, Xanthi I, Lingappan, Krithika, Moorthy, Bhagavatula
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Cytochrome P4501b1 and Hyperoxic Lung Injury
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154276/
https://ncbi.nlm.nih.gov/pubmed/29939353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy154
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