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Sexual dimorphism of the pulmonary transcriptome in neonatal hyperoxic lung injury: identification of angiogenesis as a key pathway

Bronchopulmonary dysplasia (BPD) is characterized by impaired alveolar secondary septation and vascular growth. Exposure to high concentrations of oxygen (hyperoxia) contributes to the development of BPD. The male sex is considered an independent risk factor for the development of BPD. The reasons u...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Coarfa, Cristian, Zhang, Yuhao, Maity, Suman, Perera, Dimuthu N., Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi, Moorthy, Bhagavatula, Lingappan, Krithika
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814706/
https://ncbi.nlm.nih.gov/pubmed/28818871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00230.2017
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