Hyperoxia-mediated transcriptional activation of cytochrome P4501A1 (CYP1A1) and decreased susceptibility to oxygen-mediated lung injury in newborn mice

Hyperoxia contributes to the development of bronchopulmonary dysplasia (BPD) in premature infants. In this study, we tested the hypothesis that newborn transgenic mice carrying the human CYP1A1-Luc promoter will display transcriptional activation of the human CYP1A1 promoter in vivo upon exposure to...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Jiang, Weiwu, Maturu, Paramahamsa, Liang, Yanhong Wei, Wang, Lihua, Lingappan, Krithika, Couroucli, Xanthi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743196/
https://ncbi.nlm.nih.gov/pubmed/29101037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.10.166
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