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Regulation of Cytochrome P450-1A1 Expression by Hyperoxia in Human Lung Cell Lines: Implications for Hyperoxic Lung Injury

Supplemental oxygen, used to treat pulmonary insufficiency in newborns, contributes to the development of bronchopulmonary dysplasia (BPD). Cytochrome P4501A enzymes are induced by hyperoxia in animal models, but their role in human systems is unknown. Here we investigated the molecular mechanisms o...

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Detalhes bibliográficos
Main Authors: Bhakta, Kushal Y., Jiang, Weiwu, Couroucli, Xanthi I., Fazili, Inayat S., Muthiah, Kathirvel, Moorthy, Bhagavatula
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646384/
https://ncbi.nlm.nih.gov/pubmed/18824009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.08.016
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