Regulation of Cytochrome P450-1A1 Expression by Hyperoxia in Human Lung Cell Lines: Implications for Hyperoxic Lung Injury

Supplemental oxygen, used to treat pulmonary insufficiency in newborns, contributes to the development of bronchopulmonary dysplasia (BPD). Cytochrome P4501A enzymes are induced by hyperoxia in animal models, but their role in human systems is unknown. Here we investigated the molecular mechanisms o...

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Главные авторы: Bhakta, Kushal Y., Jiang, Weiwu, Couroucli, Xanthi I., Fazili, Inayat S., Muthiah, Kathirvel, Moorthy, Bhagavatula
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646384/
https://ncbi.nlm.nih.gov/pubmed/18824009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.08.016
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