AUGMENTED OXYGEN-MEDIATED TRANSCRIPIONAL ACTIVATION OF CYTOCHROME P450 (CYP)1A EXPRESSION AND INCREASED SUSCEPTIBILITIES TO HYPEROXIC LUNG INJURY IN TRANSGENIC MICE CARRYING THE HUMAN CYP1A1 OR MOUSE 1A2 PROMOTERIN VIVO

Supplemental oxygen administration is frequently administered to preterm and term infants having pulmonary insufficiency. However, hyperoxia contributes to the development of bronchopulmonary dysplasia (BPD) in premature infants. Cytochrome P450 (CYP)A enzymes have been implicated in hyperoxic lung...

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Detaylı Bibliyografya
Asıl Yazarlar: JIANG, WEIWU, COUROUCLI, XANTHI I., WANG, LIHUA, BARRIOS, ROBERTO, MOORTHY, BHAGAVATULA
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123253/
https://ncbi.nlm.nih.gov/pubmed/21362406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.113
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