Effects of Dietary Fish Oil on the Depletion of Carcinogenic PAH-DNA Adduct Levels in the Liver of B6C3F1 Mouse

Many carcinogenic polycyclic aromatic hydrocarbons (PAHs) and their metabolites can bind covalently to DNA. Carcinogen-DNA adducts may lead to mutations in critical genes, eventually leading to cancer. In this study we report that fish oil (FO) blocks the formation of DNA adducts by detoxification o...

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Detalhes bibliográficos
Main Authors: Zhou, Guo-Dong, Zhu, Huiping, Phillips, Tracie D., Wang, Jianbo, Wang, Shi-Zhou, Wang, Fen, Amendt, Brad A., Couroucli, Xanthi I., Donnelly, Kirby C., Moorthy, Bhagavatula
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204992/
https://ncbi.nlm.nih.gov/pubmed/22066002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026589
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