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Role of retinoic acid in the modulation of benzo(a)pyrene-DNA adducts in human hepatoma cells: implications for cancer prevention

Carcinogen-DNA adducts could lead to mutations in critical genes, eventually resulting in cancer. Many studies have shown that retinoic acid (RA) plays an important role in inducing cell apoptosis. In this study we have tested the hypothesis that levels of carcinogen-DNA adducts can be diminished by...

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Detalhes bibliográficos
Main Authors: Zhou, Guo-Dong, Richardson, Molly, Fazili, Inayat S, Wang, Jianbo, Donnelly, Kirby C, Moorthy, Bhagavatula
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001276/
https://ncbi.nlm.nih.gov/pubmed/20888851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.09.019
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