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Modulation of benzo[a]pyrene–DNA adduct formation by CYP1 inducer and inhibitor
Benzo[a]pyrene (BaP) is a well-studied pro-carcinogen that is metabolically activated by cytochrome P450 enzymes. Cytochrome P4501A1 (CYP1A1) has been considered to play a central role in the activation step, which is essential for the formation of DNA adducts. This enzyme is strongly induced by man...
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| Gepubliceerd in: | Genes Environ |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5385587/ https://ncbi.nlm.nih.gov/pubmed/28405246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-017-0076-x |
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